Acute & Sub Acute Toxicity Studies of Hydroalcoholic Extract of Solanum Xanthocarpum Whole Plant

نویسندگان

چکیده

The present study is designed to evaluate the safety of aqueous: methanolic (40:60) extract Solanum xanthocarpum whole plant (SXWP) by determining its potential toxicity after acute and subacute administration in male wistar albino rats. Medicinal plants might deliver a few organic activities people, but generally very little known about their toxicity. Though, should be overriding criterion selection medicinal for use healthcare systems, several drugs produce obvious signs which are used traditional system medicine. purpose testing provide adequate database make decision concerning toxicology properties chemicals commercial products decide whether drug or will safe not.
 Results concluded that SXWP beneficial effect on some blood parameters upon oral administration. Biochemical parameter such as total protein content was changed may not lowering lipid profile can long term use. There were no significant change other serum proved use, kidney too remain unchanged. Further studies needed verify low, medium high dose chronic extract.
 Keywords: Methanolic, Extract, xanthocarpum, Toxicity, Chronic, Acute

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ژورنال

عنوان ژورنال: Journal of Biomedical and Pharmaceutical Research

سال: 2022

ISSN: ['2279-0594', '2589-8752']

DOI: https://doi.org/10.32553/jbpr.v11i5.920